Introduction: Photothermal therapy (PTT) is a nanotechnology-assisted cancer hyperthermia approach in which the interaction between laser light and plasmonic nanoparticles generates a localized heating for thermoablation of the tumor. Recent efforts in the area of PTT follow two important aims: (i) exploitation of targeting strategies for preferential accumulation of plasmonic ...

Introduction: Glioblastoma multiform is the most common malignant brain tumor, with an invasive nature. Despite the development of conventional therapies such as surgery, radiotherapy and chemotherapy, because of high recurrence rates, the prognosis remains very poor. Over the last decade, nanotechnology has represented an innovative method as nanoparticle-based drug delivery ...

There is a renewed focus on developing formulation strategies for the regional drug targeting. Magnetic drug targeting provides an innovative approach that may include two and three dimensional arrays of magnetic drug delivery systems. Applications of magnetic microsphere-based drug delivery include chemotherapy, arthritis, gene, and cell transplantation therapy. This article describes differen...

There is an ongoing struggle to develop efficient drug delivery and targeting methods within the central nervous system. One technique known as intrathecal drug delivery, involves direct drug infusion into the spinal canal and has become standard practice for treating many central nervous system diseases due to reduced systemic toxicity from the drug bypassing the blood-brain barrier. Although ...

avicenna (980 – 1037 ad) known as the prince of physicians in the west was one of the most prominent persian thinkers, philosophers, and physicians. owing to his interests in cardiology, he authored considerable works on different aspects of cardiology. “resaley-e-ragshenasi” (book on pulsology) and”kitab al-adviyt- ol-qalbiye” (the book on drugs for cardiovascular diseases) are avicenna’s grea...

Objective: Magnetic fluid hyperthermia is a technique in which thermal energy is generated by magnetic nanoparticles (MNPs) that are excited by an alternating magnetic field (AC field). During hyperthermia, in-vivo monitoring of elevation of temperature relies on invasive insertion of conventional thermometers, or employment of thermo-sensitive cameras that lack high precision....

Image-guided and target-selective modulation of drug delivery by external physical triggers at the site of pathology has the potential to enable tailored control of drug targeting. Magnetic microbubbles that are responsive to magnetic and acoustic modulation and visible to ultrasonography have been proposed as a means to realize this drug targeting strategy. To comply with this strategy in vivo...